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Due to the capability of rapid bioaccumulation, lower degradability rate and long biological half-life, Pb is of great concern in the food safety-security (FSS) debate ( It is well known that high soil accumulation of Pb is a possible hazard to all soil-related lives (Zhuang et al., 2009)

Heme oxygenase 1 is required for mammalian iron reutilization

91%) and class B (9% vs

Such cells exhibit certain unique biological features (such as stemness, slow cell cycle/quiescence, multidrug-resistance and/or epigenetic/metabolic alterations) that are inherently tolerated to the treatments (partially drug-resistant) (Miranda Furtado et al., 2019