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Additionally, HuR deficiency resulted in pronounced mitochondrial structural abnormalities and dysfunction at 2 and 6 hours, accompanied by reduced expression of the mitochondrial fission and fusion proteins Drp1 and Mfn2, increased mitochondrial protein release, and enhanced hepatocyte death

279 These data confirmed the powerful ability of cfDNA/ctDNA as a diagnostic tool for primary breast cancer

Furthermore, the released DOX impedes RNA and DNA synthesis within tumor cells, contributing to a synergistic antitumor therapy that combines CDT and CT

While high UA may accelerate the development of diabetes and impair glucose tolerance, it is insufficient to solely induce diabetes