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Work in rats using in vivo oxygen (O 2 ) amperometry similarly showed increased O 2 responses to rewards as a function of increased required effort to obtain them

2.2 Saponins/triterpenes 2.2.1 Panax ginseng ginsenoside Rg1 Ginsenoside Rg1 (G-Rg1) enhances neuronal survival by activating the PI3K/Akt anti-apoptotic signaling pathway (35)