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Hypothyroidism that is not controlled can eventually lead to the following complications: Heart problems Mental health issues Peripheral neuropathy Myxedema Infertility Birth defects Untreated hyperthyroidism can lead to complications such as: Heart problems Brittle bones Eye problems Thyrotoxic crisis Thyroid Surgery The experienced surgeons at Fort Worth ENT perform minimally invasive thyroid surgery

Debes et al., 2006)

For patients exhibiting resistance to conventional therapy, we advocate combination regimens that include NET-targeting agents (e.g., DNase I, PAD4 inhibitors), ferroptosis inducers, or nanoparticle-based drug delivery systems that overcome stromal barriers

Preparation and immunological activity of polysaccharides and their derivatives