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MAX Study: a randomized, placebo-controlled trial of the health effects of antioxidant vitamins and mineralsArch Int Med, 164 (2004), pp

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Some MeHg in tissues interacts with small molecular nucleophiles, such as glutathione (GSH) produced by glutamate-cysteine ligase (GCL), in the absence and presence of GSH S -transferase (GST), and these interactions are referred to as phase II reactions and result in the formation of GSH adducts, which are excreted into the extracellular space through multidrug resistance-associated protein (MRP) in phase III reactions 9