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Treatment of 7 with excess EtSH (20 equiv) quantitatively generated dual-adducts 9 as a pair of diastereoisomers in 30 min (Fig

Open-search mass spectrometry strategies overcome the limitations of conventional database-dependent approaches, facilitating the discovery of novel modification forms and previously unrecognized interacting proteins, thereby expanding the understanding of crotonylation-mediated networks

The high abundance and rapid and steady increase of glutathione observed in this study indicate that oxidized GSSG can serve as the oxidant for class III peroxidases for ROS production