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Description

The mice had ad libitum access to food and water and were housed under a 12 h light/dark cycle

On the other hand, ginkgo and some flavonoids may inhibit CYP3A4 or Pg-pg, leading to increased drug exposure and an increased risk of toxicity, such as myelosuppression, neuropathy, or hepatotoxicity (203)

To counteract these detrimental effects, cells rely on precise regulatory mechanisms to maintain balanced Ca 2 + levels, ensuring proper cellular function while minimizing the risk of toxicity (Nava et al., 2020