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Radermacher J, Jentsch D, Scholl MA, et al

Fully revised and updated in January 2016 by Markus Horneber

Jul 2021;15(3):189-196

This leading to the release of ions and metabolites, production of ROS, cessation of oxidative phosphorylation, followed by ATP hydrolysis, loss of matrix solutes, and mitochondrial decomposition (Rasola et al., 2010)