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Withania somnifera: progress towards a pharmaceutical agent for Immunomodulation and cancer therapeutics

The key driver of results is sustained supplementation over weeks rather than a single well-timed dose

10.1016/j.redox.2019.101418 233 SinghG.KesharwaniP.Kumar SinghG.KumarS.PuttaA.ModiG

As an example, Mndez et al demonstrated rhythmic Cxcl12 oscillations regulated by clock genes through the circadian regulation of noradrenaline secretion