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The data show that the C159S variant resolves an additional state that is not observed with the SmTGR U597C enzyme presumably as flavin reduction in this form of the enzyme is rapid and this absorption feature is overlapped and additive with the thiolate-FAD charge transfer (Smith et al., 2023)

[DOI] [PubMed] [Google Scholar] 198.Sins J.W.R., Fijnvandraat K., Rijneveld A.W., Boom M.B., Kerkhoffs J.L., van Meurs A.H., De Groot M.R., Heijboer H., Dresse M.F., Ferster A., et al

Binienda, A., Ziolkowska, S

Conclusions: The impact of high IGF-1 and IGF-1R on prognosis and immune infiltrates differs across cancer types