glutathione-s-transferase from the pathogenic fungus coccidioides immitis Frontiers Schematic representation of the structure

Thiamine hydrochloride has neuroprotective and anti-inflammatory effects

Increased neuronal excitability was observed in paclitaxel-treated DRG neurons, a condition that could be completely inhibited by pharmaceutical blockade of MNK-eIF4E signaling using eFT508 (Megat et al., 2019)

doi: 10.1146/annurev.pp.33.060182.000445 27 Exposito-RodriguezM.LaissueP

Following the discovery that MMS19 directly interacts with enzymes that regulate the maintenance of genome integrity and high-fidelity transfer of genetic information including helicases, primase, polymerases, and glycosylases, there is a very clear connection between Fe-S biogenesis through the late-acting CIA complex and DNA metabolism (Stehling et al., 2012)