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For exercise performance and VO2 max improvement, the evidence from human exercise studies suggests that MOTS-c's acute rise following high-intensity training is part of the adaptive signal driving mitochondrial biogenesis and cardiovascular remodeling

For serious injuries or aggressive recovery goals, this efficiency may be important

In many instances, the terms steroid injection, cortisone and corticosteroids are used interchangeably

While the science on whether this local application significantly outperforms systemic is still developing, the anecdotal reports from the research community are what keep this method at the forefront of the conversation