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However, the real effects of L-carnitine supplementation, taking into account its above-mentioned positive and possibly negative properties ( via TMAO), on the process of atherosclerosis and atheroma plaque merit further investigations

This leads to alterations in substrate utilization and energy metabolism

However, kidney diseases, including acute kidney injury (AKI) and chronic kidney disease (CKD), impose a substantial burden on global healthcare systems due to their high mortality rates and the limited treatment options ( In recent years, the role of post-translation modification (PTM) in renal diseases has received widespread attention

(22) showed recently that L-carnitine supplementation promoted improvements in several parameters, including O2 saturation, erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), alkaline phosphatase (ALP) activity, lactate dehydrogenase (LDH), and serum creatine phosphokinase (CPK) when compared to the intervention group