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Every Other Day (EOD) Dosing Every other day dosing at slightly higher per-session amounts (e.g., 23 mg EOD instead of 1 mg daily) is also used, particularly to reduce injection frequency or manage cost

For the final stage of maturation into functional hepatocyte-like cells (HLCs), the proliferative HBs were cultured in hepatoZYME-SFM medium supplemented with 1X GlutaMAX

The invention provides an embodiment which provides a sustained concentration of copper peptide in vivo of 12 + 2 meg/ml over 24 hrs from the time of administration