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There is no shared signature of autoreactivity that would be specific for long COVID patients (118), and the functional importance of autoimmunity in PAIS such as long COVID, ME/CFS or long Lyme/PTLDS remains to be established

This impairment can cause additional issues such as increased susceptibility to infection or disease and reduced vaccine efficacy

Rifabutin act as a weaker inducer than RIF, with 23 times lower effect on CYP3A4, making drug interactions less impactful in clinical practice (AIFA - Ricerca Farmaco, 2024)

[6] Direct sulfurization [edit] The direct sulfurylation pathways for the synthesis of cysteine or homocysteine proceeds via the replacement of the acetyl/succinyl group with free sulfide (via the cysK or cysM -encoded cysteine synthase