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The adjusted odds ratio for angular stomatitis and low riboflavin status was 5.1 (95% CI: 1.55, 16.5) (Blanck et al., 2002)

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MRS for assessing response to therapy Pseudoprogression, radiation necrosis and recurrent tumour Pseudoprogression is a non-tumoral increase in the contrast-enhancing lesion that can occur within 36 months after radiotherapy or chemotherapy without significant clinical worsening and it disappears or stabilizes on subsequent MRI without any therapy change