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Notably, mutant 3, harboring combined mutations in both the arr1-N and arr1-CC sites (P88G_P91G_P121E_P124G), did not further decrease Src activation compared with mutant 1 (P88G_P91G) or mutant 2 (P121E_P124G)

Sulforaphane Attenuates Muscle Inflammation in Dystrophin-Deficient Mdx Mice via NF-E2-Related Factor 2 (Nrf2)-Mediated Inhibition of NF-b Signaling Pathway

Due to the considerable diversity in drug responses, that is, the fact that the same pharmacological treatment can produce varying levels of efficacy and toxicity across individuals, the application of pharmacogenetics becomes essential

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