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C., Zoulim, F., Hou, J

113 In patients with IPAH, elevated levels of O 2 and ascorbate lead to increased PHD activity and reduced HIF-1 protein levels

As melanomas evolve they do not always pass through discernable evolutionary phases but can seemingly skip individual phases and can even appear without any apparent precursor lesion

CCL2 recognizes CCR2 receptors on myeloid cells, promoting their migration across the BBB, where they differentiate into inflammatory macrophages and dendritic cells [28]