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In a sample of 1,092 men and women without dementia followed for an average of 10 years, those with higher plasma homocysteine levels at baseline had a significantly higher risk of developing Alzheimer's disease and other types of dementia

Long journeys, disrupted sleep, time-zone changes, and irregular eating habits may lead to fatigue

However, this approach may give a false sense of effective medical intervention for both the patient and provider, thereby diverting attention away from further evaluation and appropriate diagnosis