cd38 inhibitor benefits with 5-amino-1mq blocks an enzyme called NNMT, and the mechanism is real, but NNMT overexpression does not track body fat. It tracks insulin resistance. Non-diabetic individuals at BMI 33 had normal NNMT. And Frontiers | Monoclonal anti-CD38 therapy
Frontiers Monoclonal anti CD38 therapy in human myeloma: retrospects and prospects US20200102274A1 Quinoline derived small molecule inhibitors of nicotinamide n methyltransferase (nnmt) and uses thereof Google Patents A Potent and Specific CD38 Inhibitor Ameliorates Age Related Metabolic Dysfunction by Reversing Tissue NAD+ Decline: Cell Metabolism CD38 as theranostic target in oncology Journal of Translational Medicine Springer Nature Link
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