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Epilepsia 46 , 849857 (2005)

Indeed, increased levels of proinflammatory cytokines, including IL-6, IL-1, IL-17A, and IL-22, are observed in psoriasis, leading to excessive ROS generation from both endogenous and exogenous sources, resulting in increased oxidative stress

7:ENEURO.545ENEURO.519

Furthermore, it was demonstrated that the overexpression of PINK1 promoted neuronal activity and protected neuronal integrity ( A substantial body of evidence indicates the presence of mitochondrial fragmentation in neuronal cells in the brains of HD patients, in which the expression levels of the mitochondrial fission/fusion proteins Drp1, Fis1, and Mfn are significantly altered (Shirendeb et al., 2012)