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The decrease in volume of distribution is due to the decreased renal and skeletal muscle mass and consequent decreased tissue binding of digoxin to Na + /K + -ATPase

"Association of nicotinamide-N-methyltransferase mRNA expression in human adipose tissue and the plasma concentration of its product, 1-methylnicotinamide, with insulin resistance." Diabetologia

Accessed October 24, 2017.

You cannot have a vitamin B12 injection if: You are sensitive to any of the excipients, which are - acetic acid, sodium chloride, sodium hydroxide, and water for injections