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Signal Transduct Target Ther 8(1):372

Antioxidants 7 (5), 62 (2018)

3.2.5 Myocardial fibrosis and MI The activation of the RAAS system primarily drives myocardial fibrosis, exerting its biological effects by increasing both anterior and posterior cardiac loads through the release of angiotensin II (Ang II), aldosterone, and other bioactive substances