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Differential gene expression analysis was performed on the different subgroups with a base mean value of expression greater than 1, log2 fold change greater than 0.6 and an adjusted p -value less than 0.1 using the DESeq2 pipeline 124

Rats were randomly divided into a sham-operated (sham) group, MCAO model group, and DZXI-treated (DZXI) group ( n = 10 rats each group)

FIGURE 2 3.1.1 Mechanism of iron overload-mediated ferroptosis involved in ischemic stroke Iron overload is considered a major cause of ferroptosis following IS (Figure 2B

The genotypes section below includes genetic variants associated with liver problems from acetaminophen, but please keep in mind that more research is needed on this topic to fully understand individual risk