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On day 8, the mean tumor diameters reached 2 mm, and the mice were randomly divided into 4 groups for injections ( n = 6)

In addition, Jin and Chen (142) found that in diabetic kidney disease, umbelliferone inhibits ferroptosis by activating the nuclear factor E2-related factor 2 (NRF-2)/heme oxygenase-1 (HO-1) pathway, significantly improving kidney damage and reducing ROS generation