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This is probably a dose-related effect and not clinically significant with the more common aspirin dose of 325 mg

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Jul 2010;203(1):68.e61-66

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HTRF-FRET was measured by a Mithras LB 940 Multimode Microplate Reader (Berthold Technologies, Bad Wildbad, Germany)

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As a major component in the production of mitochondrial-derived ROS, the impaired function of Complex I leads to excessive superoxide production and is involved in the pathogenesis of Parkinsons disease (PD) and various neurodegenerative diseases

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