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It has an hepatic metabolism, mainly because of the glucuro-conjugation of the molecule, with the formation of inactive metabolites

This ensures that your ruminants receive all the necessary nutrients for optimal health without any risk of over-supplementation

Acknowledgements This work was supported by the National Natural Science Foundation of China [grant numbers 82125037], Science Foundation for Distinguished Young Scholars of Jiangsu province [grant number BK20231528], Key R&D Program of Jiangsu Province [grant number BE2022815], Jiangsu Provincial Medical Innovation Center [grant number CXZX202225], Young Elite Scientists Sponsorship Program of the China Association for Science and Technology [grant number 2021-QNRC2-B17], and 333 high-level talents project of Jiangsu Province for Yang Yang [grant number BRA202202]

This leads to damage to tissue cells, including vascular ECs (Incalza et al., 2018), adipocytes (Furukawa et al., 2004), and pancreatic -cells (Gerber and Rutter, 2017)