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doi: 10.1007/s12015-021-10122-0 209 ZhengXWuYBiJHuangYChengYLiYet al

It directly engages NF-kB signaling, the master inflammatory transcription factor governing expression of IL-6, TNF-alpha, IL-1beta, COX-2, and hundreds of related mediators

SIRT3 deficiency is resistant to autophagy-dependent ferroptosis by inhibiting the AMPK/mTOR pathway and promoting GPX4 levels

GroEL/GroES or DnaK/DnaJ/GrpE system) can actively assist in correct protein folding and protect misfolded proteins from aggregation, while proteases degrade stably misfolded and aggregated protein species via ATP-dependent mechanisms (recently reviewed in [14])