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The illustration of rusting metal can be helpful for greater understanding, as you have undoubtedly observed the phenomenon at some point: Just like rusting indicates oxidative damage to metal and can shorten an objects life span and decrease its functionality, when oxidation is not contained, treated, or prevented, a similar process can occur on the cells and organs of the body

With over 300 million cases globally, the prevalence of OA is reflected by a staggering $460 billion annual treatment expenditure, which imposes a substantial economic burden on both families and society [3]

Currently, only three classes of antifungal drugs are available as primary therapies for life-threatening fungal infections 3 : (1) polyenes such as amphotericin B