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Germline variants in POLE are associated with early onset mismatch repair deficient colorectal cancer

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This is one reason chronic alcohol use is associated with oxidative damage and conditions like fatty liver

Water kefir, made from gelatinous probiotic-rich grains, is a non-dairy alternative for vegans and individuals with dairy allergies, offering probiotics, prebiotics, and antioxidants (Guzel-Seydim et al., 2021)