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Although the etiology remains unknown, it has been considered as a multifactorial disease resulting from the interaction of genetic, hormonal and environmental factors that contribute to the loss of immune tolerance [3,4,5]

[5] The agency has 223 field offices and 13 laboratories located across the 50 states, the United States Virgin Islands, and Puerto Rico

It was shown that chronic treatment with rapamycin leads to significant alterations in miRNA profiles and these changes correlate with resistance to rapamycin

Conclusion: Regional perfusion assessed on post-EVT DSA is associated with 90-day functional outcome after acute ischemic stroke and suggests superior predictive performance compared to eTICI