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Molecular dynamics (MD) simulations using platforms like GROMACS or AMBER can elucidate the stability and interaction dynamics of polyphenol candidates (curcumin, EGCG, resveratrol) with ADrelated targets such as amyloid, tau protein, and acetylcholinesterase, leveraging crystallographic data from PDB entries (Gheidari et al

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Drug- and toxin-induced injury is an important diagnostic consideration in dogs and cats presenting for acute hepatitis and hepatic necrosis

Ethnopharmacological knowledge can guide the design of synergistic phytochemical combinations that move beyond single compound interventions toward standardized multi component formulations with complementary actions on redox balance, membrane biology, and immune modulation (Yang et al., 2020)