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Finally, by utilizing an appropriate isotype control, we validated the specificity of PKC coimmunoprecipitation with Pin1 ( Figure S1B )

By pairing SS-31 with NAD+, researchers can investigate whether restoring mitochondrial structure allows for more efficient energy production in senescent cell models

8.2 Endogenous repair Given the limitations of exogenous MSC/disc stem cell transplantation, strategies to activate endogenous nucleus pulposus-derived stem cells (NPMSCs) to participate in intervertebral disc degeneration (IDD) repair have become a research hotspot