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Although compounds such as vitamins, polyphenols, and plant-derived molecules have demonstrated promise in preliminary studies, more comprehensive clinical trials are needed to confirm their therapeutic value, determine optimal dosages, and assess long-term safety

In the human body, L-carnitine transports fatty acids to the"powerhouses" of the cell (mitochondria), where they are "burned" to generate energy

And the whole, yeah, the whole story, short is basically when I discovered that article, I started the first self-experiments

The PDHc can be inactivated by the PDH kinase (PDK) through phosphorylation of three serine residues of the E1-subunit, while activation is achieved by the phospho-PDH phosphatase (PDP1), which is dependent on the mtCa 2+ concentration