(2015), BioMed Research International 2015:648108, PubMed 26236730 Statistics from research literature Discovered by Loren Pickart in human blood plasma in 1973 , as a factor extending the longevity of cultured liver cells The smallest peptide with documented pharmacological activity: 3 amino acids (Gly-His-Lys) + one Cu ion Molecular weight: 402 Da EU cosmetic INCI name: Copper Tripeptide-1 (registered in EU Commission CosIng database) Gene expression modulation: 4 000 human genes (Connectivity Map dataset, Pickart 2015) Plasma level in healthy humans declines from ~200 ng/mL at age 20 to ~80 ng/mL at age 60 (62 % decrease) Most-studied bioactivities: fibroblast proliferation , type I/III collagen synthesis , antioxidant activity (SOD upregulation) Reference sources (PubMed) Pickart L., Vasquez-Soltero JM., Margolina A
Archived from the original on February 12, 2013
Traditional fat burners: Pros: Cheap, readily available, immediate effects Cons: Stimulant side effects (jitters, anxiety, sleep disruption), tolerance develops quickly, effect stops when you stop taking them AOD 9604: Pros: No stimulant effects, no tolerance, maintains effectiveness, targets fat directly, minimal side effects Cons: More expensive, requires injection, slower onset of effects Most people find AOD 9604 more effective and sustainable than traditional fat burners, especially for significant fat loss goals
At Better Med Spa, AOD9604 is framed as a potential nudge for fat metabolism that only makes sense when layered onto disciplined nutrition, movement, and sometimes GLP1 or other medical therapies