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Sprung, C

J Mater Chem B 7:1824

In the cochlea, it has been hypothesized that cochlear mitochondrial redox imbalance and mtDNA mutations and deletions may be synergistically involved in ARHL ( Mitophagy maintain mitochondrial homeostasis Mitochondria in cells with high energy demand are often numerous, forming an expansive dynamic functional and structural network that requires certain mechanisms to maintain the homeostasis of the mitochondrial network

Moreover, PDA cells can efficiently recycle various metabolic substrates through the activation of different salvage pathways such as autophagy and micropinocytosis 6,9