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Vascular occlusion by neutrophil extracellular traps in COVID-19

We therefore hypothesized that the overall perturbations to the gsh2 extracellular environment were collectively sufficient to block melanogenesis, either by preventing the conversion of L-DOPA into melanin and/or by inhibiting fungal laccase 24,51

It disrupts the structural integrity of cell membranes, but due to the incidence of hepatotoxicity, the drug was eliminated from clinical trials [151]