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Oxidative stress induced by hepatitis viruses, such as HBV and HCV, contributes to the development of hepatocellular carcinoma 82

Overall, our results show that a subset of chloroacetamides (including SCLA1, SCLA2 and SCLA3) engages GPX4 to induce ferroptosis in senescent cells

Visseaux, B., Damond, F., Matheron, S., Descamps, D

Within this complex, RAPTOR interacts with the N-terminal region of mTOR, playing a critical role in complex assembly, subcellular localization, stability, and substrates recruitment