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The new boosters target both the original strain that emerged in China more than two years ago, which scientists refer to as the "wild type," and omicron BA.4 and BA.5, which are now the dominant variants in the U.S

Epileptic astrocytes are also characterized by partial loss of glutamate synthetase and reduced GABA availability 317 , increased expression of astrocyte-specific adenosine kinasewhich limits adenosine levels and further decreases adenosine A1 receptor-mediated inhibition 318 loss of AQP4 polarization at astrocytic endfeet 319 and downregulation of astrocytic Cx43

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