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Furthermore, it has been reported previously that TGFb2 was elevated in the vCSF of PD patients in comparison to healthy controls [47]

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cAMP level can regulate the protein kinase A (PKA)-dependent activation of the cAMP response element-binding protein (CREB), which in turn upregulates the expression of PGC1 and inhibits LC3-II (Herzig and Shaw, 2018)