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One of the key reasons that CSCs remain difficult to eliminate is their intrinsic plasticity, allowing them to transition between quiescent and proliferative states, adopt epithelial or mesenchymal phenotypes, and reprogram their metabolic and epigenetic landscapes in response to therapeutic stress

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Rhee, F.S

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If you have severe abdominal pain (that may spread to the back), persistent vomiting, or signs of pancreatitis stop using and contact your healthcare provider immediately

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Its mechanism of action upstream stimulation of pituitary GH secretion rather than exogenous GH replacement preserves the regulatory architecture of the hypothalamic-pituitary axis, making it a pharmacologically distinct tool from direct rhGH administration in ageing research models

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