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In some embodiments, the invention encompasses a method of providing muscular therapy by contacting a cell expressing NNMT with a NNMT inhibitor (such as a cation of Formula I or IA, or otherwise disclosed herein) and one or more chemical entities (e.g., nicotinamide riboside, nicotinamide mononucleotide) that increases intracellular NAD+ levels to provide muscular therapy

In conclusion, maintaining adequate vitamin B12 intake is vital for blood health, neurological function, DNA synthesis, energy production, heart health, and mental well-being

Rather than focusing only on lifespan, it emphasizes healthspan, how well you feel and perform as you age, using screening, monitoring, and individualized wellness strategies

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