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NRTP induced fibrosis through the CXCL10IL18R1 COL1A1 pathway Fibrosis severely impairs ovarian function and is the main feature of reproductive aging 23 and polycystic ovary syndrome 24

An open-label, single-arm and phase IIa clinical study has been designed for investigating the efficacy of combining focused ultrasound-driven BBB disruption with bevacizumab in the treatment of glioblastoma patients

Res 3 , 9498 (2015)

Phenothiazines also have peripheral and/or central antagonistic activity against alpha-adrenergic, serotonergic, histaminic (H1-receptors), and muscarinic receptors