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the therapeutic agent may be formulated with and/or co-administered with one or more beta lactam antibiotics

Resistance to the cellular effects of insulin is a significant contributor to obesity (125) and gradually leads to a failure of pancreatic -cell function, which inevitably results in impaired insulin secretion due to a progressive loss of insulin sensitivity of peripheral target tissues

Retatrutide is an unapproved investigational triple agonist (GLP-1, GIP, glucagon receptors) not licensed by the MHRA, EMA, or FDA for routine clinical use