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Description

Perinatal testosterone exposure potentiates vascular dysfunction by ER suppression in endothelial progenitor cells

A.AebischerP.et al

Instead of initiating the treatment 1 week after implantation of cells [as was done by Pothula et al., 11 ] the tumours in this study were allowed to develop for 4 weeks (at which time tumours are well established and have metastasised) and the mice were then treated for 6 weeks with HGF/c-MET inhibitors and gemcitabine as single agent, or in dual or triple combinations