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Corresponding authors of publications were contacted for missing data

Beyond urea and tretinoin, other topical therapies also showed useful effects in randomized trials

S1C, clusters 1, 3, and 19 represent TECs and enriched pathways of Metabolism pathways, Glyoxylate and dicarboxylate metabolism, PPAR signaling, and other pathways during the injury, which provided us with hints for subsequent studies