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Homocysteine can also transform into homocysteine thiolactone in a self-loop reaction, which boosts the generation of reactive oxygen species (ROS) with the development of oxidative stress (Silla et al

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Many illnesses are related to oxidative stress arising from the affected tissue losing the capacity to maintain glutathione at adequate levels (dysfunctional homeostasis)

the invention encompasses cations of Formula I, wherein: R 1 is C 1-4 alkyl R 2 , R 3 , R 4 , and R 5 are independently selected from the group consisting of: H, C1-4 alkyl, halogen-substituted C 1-4 alkyl, NR 9 R 10 , and CN