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204,207 These results raise the possibility that RNAP II and mtRNAPs might function as both sensors and executors, which sense NAD + /NADH ratios and induce the NAD + capping to regulate the gene expression, leading to the crosstalk between cellular NAD + metabolism and transcriptional activity

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10.1021/bi00088a023 30 RengbyO.ChengQ.VahterM.JrnvallH.ArnrE

Furthermore, the enzymatic activity of catalase increased significantly in the epididymal tissues, while, on the other hand, the activity of manganese superoxide dismutase (Mn SOD) and glutathione peroxidase (GPX) decreased in the seminal vesicle