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Figure 4 ALA significantly inhibits the expression of signaling proteins of ER stress following CSD In order to further investigate whether ALA would exert the hepatoprotective effects through modulating the activities of endoplasmic reticulum stress (ER stress) following CSD, the expressions of signaling proteins involved in the process of ER stress (such as ATF6, IRE1, and PERK) were quantitatively examined by the immunoblotting analysis

Furthermore, our previous analysis of 19 tagSNPs in the NNMT gene sequences of Chinese Han patients revealed a significant association between the variant at rs1941404 and hyperlipidemia