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G., Ores, J

Differential expression profile of lipid metabolism genes in KO livers following chronic alcohol feeding Hepatic quantitative real-time PCR analysis revealed that in KO mice fed control chow diet, genes promoting lipid synthesis ( Srebp1 , Fasn , Scd1 , and Fads1 ) were suppressed (Fig

At the post-translational level, just as CBP/p300-mediated acetylation of Lys within the Neh1 domain increasing NRF2-dependent transcription, SIRT1 mediates Lys deacetylation, antagonizing the NRF2 signal [234]